Ribosomal protein S7



Ribosomal protein S7 (RPS7) is one of the 22 proteins which belong to the small subunit of the bacterial ribosome. It binds to 16S RRNA and is one of the proteins responsible for the initiation of the 30S particle assembly. It crosslinks with tRNA at the A- and P-sites. The images at the left and at the right correspond to one representative RPS7, i.e. the crystal structure of Ribosomal protein S7 from Thermus thermophilus (2zm6, chain G).

3D Structures of Ribosomal protein S7
Update June 2011

RPS7
1iqv – RPS7 – Pyrococcus horikoshii

1rss – TtRPS7 - Thermus thermophilus

1hus – RPS7 – Geobacillus stearothermophilus

S7 in small ribosomal subunit
2zm6, 1n36, 1j5e, 3oge, 3ogy, 3ohc, 3ohd, 3ohy, 3oi0, 3oi2, 3oi4, 3oto - TtRPS7 in 30S ribosomal subunit+THX+16S RRNA – Thermus thermophilus

2vqe, 2vqf, 2uuc, 2e5l, 2uu9, 2uua, 2uub, 3pyn, 3pyq, 3pys, 3pyu - TtRPS7 in 30S ribosomal subunit+16S RRNA+RNA fragment

3kc4 – EcRPS5 in 30S ribosomal subunit - Escherichia coli

3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 1pnx, 3oaq, 3oar, 3ofa, 3ofb, 3ofo, 3ofp, 3ofx, 3ofy, 3or9, 3ora - EcRPS7 in 30S ribosomal subunit+16S RRNA

1i94, 1fka - TtRPS7 in 30S ribosomal subunit+16S RRNA

1p87, 1p6g - EcRPS7 in 30S ribosomal subunit+16S RRNA – Cryo-EM

3bbn - RPS7 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach

S7 in small + large ribosomal subunit
1ml5 - EcRPS7 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM

S7 in small ribosomal subunit+ chain release factor
3mr8, 3ms0 – TtRPS7 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA

3d5a, 3d5c - TtRPS7 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA

2b64 - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1

2b9m - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2

2x9r, 2x9t, 2wh1, 2wh3 - TtRPS7 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA

3f1e, 3f1g - TtRPS7 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA

S7 in small ribosomal subunit+tRNA+mRNA
2hgi - TtRPS7 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet

2hgp - TtRPS7 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA

2i2p, 2i2u - EcRPS7 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA

2hgr - TtRPS7 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA

1yl4 – TtRPS7 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator

1pns - EcRPS7 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA

1xnq, 1xnr - TtRPS7 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA

S7 in small ribosomal subunit+A-site tRNA
2uxd, 2uxc - TtRPS7 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA

1n32, 1n33 - TtRPS7 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA

1n34 - TtRPS7 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA

1xmo, 1xmq - TtRPS7 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA

2uxb - TtRPS7 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA

S7 in small ribosomal subunit+P-site tRNA
3i8g - TtRPS7 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA

3i8h, 3i9b, 3i9d - TtRPS7 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA

1ibk - TtRPS7 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA

2wwl - EcRPS7 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - Escherichia coli

3i1q - EcRPS7 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA

3i1s, 3i1z, 3i21 - Ecv in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA

S7 in small ribosomal subunit+A-site tRNA+P-site tRNA
1ibl, 1ibm - TtRPS7 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA

S7 in small ribosomal subunit+P-site tRNA+E-site tRNA
2ow8 - TtRPS7 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA

2b9o - TtRPS7 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA

2qnh - TtRPS7 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA

2wdg, 2wdh, 2wdk, 2wdm - TtRPS7 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe

S7 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA
2gy9, 2gyb - EcRPS7 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM

1jgo, 1jgp, 1jgq, 1gix - TtRPS7 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA

3e1a, 3e1c - EcRPS7 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA

S7 in small ribosomal subunit + antibiotics
1i95, 1i97, 2hhh, 2f4v, 3knn - TtRPS7 in 30S ribosomal subunit+16S RRNA+antibiotic

1hnw, 1hnx, 1hnz, 1fjg - TtRPS7 in 30S ribosomal subunit+16S RRNA+mRNA fragment+antibiotic

2qbb, 2qb9, 1vs5, 1vs7, 2qan, 2qal, 2qou, 2qow, 2qoy, 2qp0, 2z4k, 2z4m - EcRPS7 in 30S ribosomal subunit+16S RRNA+antibiotic

2j00, 2j02 - TtRPS7 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA

3knj, 3knh - TtRPS7 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin

3knl, 3knm - TtRPS7 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin

S7 in small ribosomal subunit + ribosome recycling factor
2qbd, 2qbf - EcRPS7 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor

3r8n, 3r8o – EcRPS6 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor + mRNA + tRNA

2qbh, 2qbj - EcRPS7 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin

2v46, 2v48 - TtRPS7 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet

S7 in small ribosomal subunit + elongation factor
2wri, 2wrk, 2xsy, 2xuy - TtRPS7 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G

2wrn, 2wrq - TtRPS7 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4

2xqd – TtRPS7 in 30S ribosomal subunit+THX+E-site tRNA+mRNA +16S RRNA+elongation factor TU-B

3fic - TtRPS7 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A

3izv – EcRPS7 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+elongation factor TU

3izw – EcRPS7 in 30S ribosomal subunit+A-site tRNA Phe +mRNA +16S RRNA+elongation factor TU

2y0u, 2y0w, 2y0y, 2y10, 2y12, 2y14, 2y16, 2y18 -TtRPS7 i 30S subunit+THX+A-site t`RNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU

3fih - EcRPS7 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU

3huw, 3huy - TtRPS7 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P

S7 in small ribosomal subunit + translation initiation factor
1i96 - TtRPS7 in 30S ribosomal subunit+THX+IF3+16S RRNA

1hr0 - TtRPS7 in 30S ribosomal subunit+THX+IF+16S RRNA

S7 in small ribosomal subunit + various proteins
3kiq, 3kis, 3kiu, 3kix - TtRPS7 in 30S ribosomal subunit+toxin RelE+16S RRNA

1voq, 1vos, 1vov, 1vox, 1voz - EcRPS7 in 30S ribosomal subunit+protein Y+16S RRNA

3gty – RPS7+trigger factor – Thermotoga maritima

3iz6 – RPS7 in 40S ribosomal subunit+RACK1 – wheat – Cryo EM

2xzm, 2xzn - RPS7 in 40S subnit+18S RRNA+RACK1 - Tetrahymena thermophila

1x18 – TtRPS7+TtRPS2+TtRPS11+TtRPS18+ERA GTPase+16S RRNA fragment

2xfz, 2xg1 – TtRPS7 in 30S ribosomal subunit+colicin E3+E-site tRNA+mRNA+16S RRNA

3j00 – EcRPS7 + 16S RRNA + FTSQ + apolipoprotein A-I

S7 in part of small ribosomal subunit
1qd7 – TtRPS7+TtRPS4+TtRPS6+TtRPS5+TtRPS8+TtRPS15+TtRPS17+TtRPS20+16S RRNA fragment

1dv4 – GsRPS7+TtRPS5+16S RRNA